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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dace52be5004e1736c75d3b79debbbec4aa1d1d3653a7e428f1b21500b89d111' 
  AND token = 'JBEuXRtSz0oqhVMWUa+ARxUNWGVzgn9vBhF0/R0kUXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}