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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9b8611193088d93b4c29b2a6d9560b6a3f04556da67469555767f840fe3205' 
  AND token = '59cmmtE2O6XsRy44tn/J+hAGN0/dxZqUcqrpinvDyAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}