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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c75d714d8ee7b4b4df8ccb1b97b4e4dc6a22935e9b6202250c0b185f43140ef5' 
  AND token = 'w1TKuSlemAo2NyjPgDMAz6Ejve3u+0tDM2PIDb5P+lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}