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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a8173c575737a62431cbc5503f484d11e24a932e0f2019f6235712f73042fc' 
  AND token = '6oKPvjlzJDRdDqqJX6tx7YO7bLOY5eLHuIf1H3OR5ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}