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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c33e66af91b57532b2c66796744221c2587cf2cdaab4ff3042e80b0e61265e' 
  AND token = 'GEXiD2GmXr60Wfeshxvk3/3lPN+tQsVDH1TFa40FUJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}