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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f3254bd090a1f066ece6f43c832b7df2217cdb72411934ba16aa86b1c6fded' 
  AND token = '+rZYpna92re12gFts/dfszMnT9ONchGnaVVTZ7Qr25Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}