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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59b326b493d1186a2f03675eb57aea05c275bdbcc31b616d8a18874edea78062' 
  AND token = 'hBSxfRbY6rhryZL0/5dB5/FCYQxI3oNtchT5t61wZkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}