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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64dc69f3b7a3335bfb67c15b776abdbd33f8c044dca82fd65a41a0b97430c172' 
  AND token = 'cpvUjP5nk3W5Fz8EmUHpoerj/DH3yBEjgn1yU6zBMOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}