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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330e2c55d596a6e4430a42b60313c3876efe43322fa57959a094f4162dde4d18' 
  AND token = 'XiE/CpH5HiRlfNhAmNHHrI4vTD+US08rUazmMXj/jB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}