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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0590c09d721bddc8b09e49f456c405c84552f3dc2f80c422b6e3f67d140aec77' 
  AND token = 'miJeHCPqirO5HbT5Sbfvq9LzzDLsKezWAFXEKV3LPSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}