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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1b77eb96ca1260f96627199cf4413cb9f384d8aff7e3e3b8508e38b7f0e611' 
  AND token = '4AcvYlLTGpf88Fd0oqEzXzltdA+Hpuc9ynsIDRSI2EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}