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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd2e9ed1757658de8921a76153c63b8f270ac31207032ffe2701ae7056892436' 
  AND token = 'W0Pjykh0AjPZGVJefeTDs9nfRTqEPpqZBQk6JRE6Ffc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}