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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35edde8b4892b7341376ceb2b84c20f852c137702c42bc19a00306fc6e8e56a4' 
  AND token = 'bRada31d1Qg4RWYy963Ix2llqD4a9WDbMGNNXCtQ1wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}