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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '806a5d835874a8b9e44c7f64d9f3c2aaf78eda9c3edebb28a3162964a00c619b' 
  AND token = 'M2ehiyXcM7/HQNvqWmoyipQgD3BumKOukoTC5PrcPw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}