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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc67f441f5130c2f3b3019109bea58457ecb2cf78a1f4fcda80cd7a49fbb6d2' 
  AND token = 'cwhf5wRnVF0uNIFB96zFHP/fKXZwa5wh4cqaVm/IQCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}