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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85f99d4d0d0761f70cfa49fcbee6e7688b627b281f6197679da8e0a752b9bb47' 
  AND token = 'h/uY+oqKxZsrs4PTs+yJ9tl72cuGHBmkpEEGcRuyy+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}