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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e62b522f3a8100a2d60dca373349f94cd20a438339239af3a2b752d06f92c9f' 
  AND token = 'BYEGz3Kaa+llp/lBz1hAsg+jbTdORgQlj/jlMus27Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}