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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2bb44c9feb812d5bac01cc9da9bf8bc21743a10e34c76a2f9f940d20d0dfcee' 
  AND token = 'QbLFUqiAqoram1qfH5gdQj8lmdbjaFNLMyH7weE2GFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}