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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f347a63a17cf23154d13fb01c5bc32d003c198c0f16d791f22a724038fa732b' 
  AND token = 'EaZH8gUS5+90a1QhNC1WiWyB7a6HXcj4DkgrAMnEjOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}