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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '967bd81cfbbcdda887ecb0edda642fd3f86a94414a1bc319f2cef6f4990754dc' 
  AND token = '6ZtytAlkI+UrYQGLGuRG+/j+s6U2GC6fdqorlaNOp6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}