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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '475e436d49f2b58049895ac2f4157ac67754b4f7a2201db4974f65cd150d413d' 
  AND token = 'n+xdyPEijAxeJl3DaJ6p+46EH+vgZazFcdSVJngl6XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}