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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9443e3d31620ffd05ff50cd91bf7f5b4cf7fa6db7496f119e30b15e90156438a' 
  AND token = 't7R0fYEEAe8v+znw6gNLAJwxreK7c2DigF3I7zlxWwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}