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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff4a464c22c27f47ee98278e801ecb3364ee3a68dce4892a9aa37d5812bd762' 
  AND token = '0Fz+ul61KPAiTQIXW0buKNu09BhBG1LZiZWrDj/ZUg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}