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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea00f9bd428dd3181511bfc01e8d80bec0b7062110def3604d53a716087f641d' 
  AND token = 'gp3g1vM9MwmVYM+11R3z4l2xp+qKeFT4ftsh2hNz5/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}