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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181237cd6fbc956003d8747045432e96773524013bcb07c0f2c2ddb04800c913' 
  AND token = 'oimzmKPmSKH3rg9KjLmwb66OD/o65Y57ouI1x7viMt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}