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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc5a1865a0317301574b7e4083553ddbcb29d597a66bb8b9e71184d4ce95c5ea' 
  AND token = 'k2J6OzGhm4SbFZWtghXwV2MUMemIca/XrAKz5kZtKRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}