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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a4d5dd6ea5b69cbf294e3998509822f167ed5d134edbd665eb509c4e76cfb8' 
  AND token = '4Rkk9rNCQzGzexw/EfkjY1ENSaiVEW8PxyZyiwmj55Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}