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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5656f6876c766e119cd95f3d37ea58545c15550db2981dd46e2614ce9942984d' 
  AND token = 'EBEttEd7C42Vk6A3RFnooVUBe+4eTxd2Wjia/W0rnfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}