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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55160f112171d6b63d43443b515191e5a2fc80df79803bd6ee6e092b6063180b' 
  AND token = 'yxGniS+9wJe1D+yjJUDS8+lFKCVSyevMddKMyiRU5Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}