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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df2f1af90be50041a8003b772fab34587ea05573a09f9060fbaa915ae7727438' 
  AND token = '4Mb+qRT6X20TEPSriOrV6aAS9LPplXK411OatsgLtRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}