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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79264e117a7820eee5e29a40600caee0ad342cd32b9cb79b0f13e11bdb600f81' 
  AND token = 'fxPP/wyx0EpXTkRGOcSkP0I7gQIqNVUSNl7oLXHJHv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}