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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '261ef80ca9719515ebe281115c6184bddb9dc83d3de6eee53ffd9703794b424e' 
  AND token = '6Du58K7R7H6mca/oXoZ72mbY1nD0BI8+WV81ExEs26Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}