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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea10467f5bbad833947da361e8cd295cc3f9a646e3c304bc15b607f5b30fa174' 
  AND token = 'NEBEg2iNf5HqUxEPCf82dLe9zQxOdqJ0OkuK5AJ6Cso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}