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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2365fa42b5e8ec953b3fea6a5ab75e15d472463a804bcf22b3e00f7df7b86268' 
  AND token = 'oco2dzTvZJa1hSu2Nun51G8m3Sd0Qg2DjYPx3ZG77Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}