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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ed4259a1c625c4c284c18a6df8168a8436591678ed36e30e582ce1b5f56e0f' 
  AND token = '60EavxDqlqAH9F5ZmKqPTYmpL2dsSBYLEtj7ov86PL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}