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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdcdeea751537de31cd84f2d586bedc4256a6e88976ccf451e0ed18d967857a4' 
  AND token = '+aNYqcPQ8rZvHwQ7lUudAdCuNgB4yuK7r38CN4UMzp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}