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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16326f0ec9c960aaf7d96d86873e8fe2b784fc3efadac93b8c83778032218225' 
  AND token = '5Yem9tQ1gnC0fX0caQaOhn001EYermFj2Une890Xyzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}