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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243a6b117d5973d3cf3a73809a78818edbf3a27335c0341a4252fc3a4129fa7c' 
  AND token = 'C/8bxS1EAxXWCGYTHOSLl1OQ1gK4Q2FZnIBG6yeig3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}