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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5e1f4665f3223f2ecd1058d800b3c6adae32949ee5ee3d0b82ff39187a14a4d' 
  AND token = 'lwi8gKqcZqMyEDKPSl9HnSdZBWbGTI9JpK2EEGJtjAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}