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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03a2e8cc84b2abfd9f7d1e5653ededd4fd2ff95a2b4d3e4214d827de8646669' 
  AND token = 'XbkcQmbj1zjjnka1CSnF+zdvTf5LQKJxk26AXE6nYoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}