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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f0e3b14a361c5039f8437863c1e8f5a3492d42468920efb8c326265082ea20' 
  AND token = 'yXWWjeU5sfis8QWbJElmYS8AUgadZZIKxJW/D8TLjBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}