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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2a6b81c48e3648af1f71d4788444c39bd225eacd59dcab433b376945f0638ec' 
  AND token = 'q1grkFZXLa9cCkg5kc+4mowEuC9PDijGHyV+HB3C06E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}