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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b646857f3e9e85cdfcd93c9e2b7cbbb240fa519260a5ee15ddbf11f6e20b93b2' 
  AND token = 'w6t3BiTa/5vQN/nnrvmXUW3lHEmak476F6LBroqRnEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}