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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2a41424dcbff1b1cecaed90011cf2cc0a2c6c2975c8a0c454e539e34205b793' 
  AND token = 'wAV/bg/Ox4RMsMBcE3h4R4ERSYILP7bR2ykINGttrM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}