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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649a4d5c224bc9bac163fb68a3bb746af286c18c4d9caec763b4dbed8f393ae7' 
  AND token = 'p5sizcWN+IlTjBXE7yhoq94P8G3vZmt8PxL5sviAKoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}