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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac695ca99191014e0a03075c30b6b9d90948490287ded68cca576af83a22690' 
  AND token = '0iMSjl17cl7XitihcT7ecpVLxowP7ftMnH200HzWaSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}