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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4842f1a6cda0aed63463cbf9b11c961a4e7d542c191f372eee27e426edecba92' 
  AND token = 'IDUK2DySgUUPj7YRCLIrpHLp+2FZhC5XuD/SIWC3ul4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}