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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b292306687b57275331e32defa78a3d7be24d8e7ba5a72d0b48a6318d1039e' 
  AND token = 'p8+a7s7o7jV4xRnzwgHMFvTMD0UtuBbHXMc/lsjIHfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}