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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666ebab3800a93b09788122064f2454d159183debe07d78bf9b987171feb5141' 
  AND token = 'FaacYfiwQWJxNZT4AT3Y1qZ1kdDW9l0Mb/VhAZHTgxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}