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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e17f6f68cd250e7070a0a06fe3ea93806e793c0766f67b44c1ef9838be477ebb' 
  AND token = 'XgGV5kT//cMN7m3Mv4DK6M2cJk0lPpTCUwVDNo7BDJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}